Indigenous Plant-Based Alternatives for Treating Cattle Skin Ailments: A Case Study from the Mnisi Tribal Authority of Mpumalanga Province, South Africa

The study was carried out in the Mnisi Tribal Authority, Mpumalanga Province, South Africa, between August and October 2021. Ethno-veterinary data were collected using pre-structured questionnaires field observations with cattle owners. analyzed summarized descriptive statistics. Frequently mentioned plants belonged to families Vitaceae (Cissus quandrangularis), Euphorbiaceae (Synadenium cupulare), Fabaceae (Dichrostachys cinerea), Solanaceae (Nicotiana batacum), Euphorbiacae (Jatropha zayheri), Apocynaceae (Sarcostemma viminate). Antimicrobial susceptibility assays ampicillin as positive control on extracts of Synadenium cupulare (aerial parts leaves), Dichrostachys cinerea (seeds/ fruits), Cissus quadrangularis leaves). Aqueous S.cupulare (L) most effective against E. faecalis lowest MIC 0.73 mg/ml, followed by aqueous an 1.36. Open wounds common ailment (35%), abscesses (23%) abrasions (17%). Documenting Indigenous knowledge can be a basis for development sustainably used medicinal area validation these plant preparations veterinary use since low cost makes them useful local communities.